Artificial Intelligence in Medicine
Volume 28, Issue 1 , Pages 27-57, May 2003

Active subgroup mining: a case study in coronary heart disease risk group detection

  • Dragan Gamberger

      Affiliations

    • Rudjer Bošković Institute, Zagreb, Croatia
  • ,
  • Nada Lavrač

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +386-61-177-3272; fax: +386-61-125-1038.
    • Jožef Stefan Institute, Ljubljana, Slovenia
  • ,
  • Goran Krstačić

      Affiliations

    • Institute for Cardiovascular Prevention and Rehabilitation, Zagreb, Croatia

Received 9 May 2002; received in revised form 11 January 2003; accepted 15 January 2003.

Abstract 

This paper presents an approach to active mining of patient records aimed at discovering patient groups at high risk for coronary heart disease (CHD). The approach proposes active expert involvement in the following steps of the knowledge discovery process: data gathering, cleaning and transformation, subgroup discovery, statistical characterization of induced subgroups, their interpretation, and the evaluation of results. As in the discovery and characterization of risk subgroups, the main risk factors are made explicit, the proposed methodology has high potential for patient screening and early detection of patient groups at risk for CHD.

Keywords:  Coronary heart disease, Active mining, Machine learning, Subgroup discovery, Risk group detection, Non-invasive cardiovascular tests

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PII: S0933-3657(03)00034-4

doi:10.1016/S0933-3657(03)00034-4

Artificial Intelligence in Medicine
Volume 28, Issue 1 , Pages 27-57, May 2003