Artificial Intelligence in Medicine
Volume 41, Issue 2 , Pages 145-150 , October 2007

Robust effects of Tsr–CheBp and CheA–CheYp affinity in bacterial chemotaxis

Received 2 December 2006 ,Revised 31 July 2007 ,Accepted 31 July 2007.

References 

  1. Foynes S, Dorrell N, Ward SJ, Stabler RA, McColm AA, Rycroft AN, et al. Helicobacter pylori possesses two CheY response regulators and a histidine kinase sensor, CheA, which are essential for chemotaxis and colonization of the gastric mucosa. Infect Immun. 2000;68(4):2016–2023
  2. de Haas CJC, Veldkamp KE, Peschel A, Weerkamp F, Van Wamel WJB, Heezius ECJM, et al. Chemotaxis inhibitory protein of Staphylococcus aureus, a bacterial antiinflammatory agent. J Exp Med. 2004;199(5):687–695
  3. Falke JJ, Bass RB, Butler SL, Chervitz SA, Danielson MA. The two-component signaling pathway of bacterial chemotaxis: a molecular view of signal transduction by receptors, kinases, and adaptation enzymes. Annu Rev Cell Dev Biol. 1997;13:457–512
  4. Falke JJ, Hazelbauer GL. Transmembrane signaling in bacterial chemoreceptors. Trends Biochem Sci. 2001;26(4):257–265
  5. Barkai N, Leibler S. Robustness in simple biochemical networks. Nature. 1997;387(6636):913–917
  6. Korobkova E, Emonet T, Vilar JMG , Shimizu TS, Cluzel P. From molecular noise to behavioural variability in a single bacterium. Nature. 2004;428(6982):574–578
  7. Mello BA, Tu Y. Quantitative modeling of sensitivity in bacterial chemotaxis: the role of coupling among different chemoreceptor species. Proc Natl Acad Sci USA. 2003;100(14):8223–8228
  8. Shimizu TS, Le Novere N, Levin MD, Beavil AJ, Sutton BJ, Bray D. Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis. Nat Cell Biol. 2000;2(11):792–796
  9. Alon U, Surette MG, Barkai N, Leibler S. Robustness in bacterial chemotaxis. Nature. 1999;397(6715):168–171
  10. Yi TM, Huang Y, Simon MI, Doyle J. Robust perfect adaptation in bacterial chemotaxis through integral feedback control. Proc Natl Acad Sci USA. 2000;97(9):4649–4653
  11. Bray D, Levin MD, Morton-Firth CJ. Receptor clustering as a cellular mechanism to control sensitivity. Nature. 1998;393(6680):85–88
  12. Sourjik V, Berg HC. Receptor sensitivity in bacterial chemotaxis. Proc Natl Acad Sci USA. 2002;99(1):123–127
  13. Asakura S, Honda H. Two-state model for bacterial chemoreceptor proteins. The role of multiple methylation. J Mol Biol. 1984;176(3):349–367
  14. Morton-Firth CJ, Shimizu TS, Bray D. A free-energy-based stochastic simulation of the Tar receptor complex. J Mol Biol. 1999;286(4):1059–1074
  15. Almogy G, Stone L, Ben-Tal N. Multi-stage regulation, a key to reliable adaptive biochemical pathways. Biophys J. 2001;81(6):3016–3028
  16. Lipkow K. Changing cellular location of CheZ predicted by molecular simulations. PLoS Comput Biol. 2006;2(4):e39
  17. Li M, Hazelbauer GL. Cellular stoichiometry of the components of the chemotaxis signaling complex. J Bacteriol. 2004;186(12):3687–3694
  18. Kott L, Braswell EH, Shrout AL, Weis RM. Distributed subunit interactions in CheA contribute to dimer stability: a sedimentation equilibrium study. Biochim Biophys Acta. 2004;1696(1):131–140

PII: S0933-3657(07)00098-X

doi: 10.1016/j.artmed.2007.07.011

Artificial Intelligence in Medicine
Volume 41, Issue 2 , Pages 145-150 , October 2007