Artificial Intelligence in Medicine
Volume 46, Issue 2 , Pages 155-163, June 2009

An integrated scheme for feature selection and parameter setting in the support vector machine modeling and its application to the prediction of pharmacokinetic properties of drugs

  • Sheng-Yong Yang

      Affiliations

    • State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan 610041, PR China
    • Corresponding Author InformationCorresponding author at: No. 1, Keyuan Road 4, Gaopeng Street, High-Tech Park, Chengdu, Sichuan 610041, PR China. Tel.: +86 28 85164063; fax: +86 28 85164060.
    • ,
  • Qi Huang

      Affiliations

    • State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan 610041, PR China
    • ,
  • Lin-Li Li

      Affiliations

    • West China School of Pharmacy, Sichuan University, Chengdu, Sichuan 610041, PR China
    • ,
  • Chang-Ying Ma

      Affiliations

    • State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan 610041, PR China
    • ,
  • Hui Zhang

      Affiliations

    • State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan 610041, PR China
    • ,
  • Ru Bai

      Affiliations

    • State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan 610041, PR China
    • ,
  • Qi-Zhi Teng

      Affiliations

    • State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan 610041, PR China
    • ,
  • Ming-Li Xiang

      Affiliations

    • State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan 610041, PR China
    • ,
  • Yu-Quan Wei

      Affiliations

    • State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan 610041, PR China

Received 11 December 2007; received in revised form 2 July 2008; accepted 4 July 2008.

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PII: S0933-3657(08)00088-2

doi:10.1016/j.artmed.2008.07.001

Artificial Intelligence in Medicine
Volume 46, Issue 2 , Pages 155-163, June 2009

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